Research & Publications
Scientific Work
Dr. Apostolakopoulou has an extensive research record and a consistent presence in the international scientific community, with publications in peer-reviewed journals including The Journal of Headache and Pain, Cephalalgia, the European Journal of Paediatric Neurology, Epilepsy & Behavior and Brain Research. Her academic work includes active participation in multicentre studies, as well as undergraduate and postgraduate teaching at the 1st Neurology Clinic of the University of Athens.
Published in peer-reviewed international journals
Selected Publications
Apostolakopoulou L, Bosque-Varela P, Rossini F, O'Sullivan C, Löscher W, Kuchukhidze G, Trinka E.
Intravenous topiramate for seizure emergencies — first in human case report.
Epilepsy & Behavior. 2023; 142:109158.
View (DOI)De Santis F, Rosignoli C, Onofri A, Braschinsky M, Sved O, Gil-Gouveia R, Oliveira R, Lampl C, Paungarttner J, Martelletti P, Wells-Gatnik W, Martins I, Mitsikostas D-D, Apostolakopoulou L, Ozge A, Narin D, Pozo-Rosich P, Muñoz Vendrell A, Prudenzano M, Ornello R.
Diagnostic tests and headache misdiagnoses in individuals with resistant and refractory migraine — data from the REFINE study.
Cephalalgia. 2026; 46.
View (DOI)Vlachos I, Moschovos C, Apostolakopoulou L, Karasavvidou K, Ntanasi E, Mamalaki E, Kugiumtzis D, Kimiskidis VK, Scarmeas N, Kyrozis A.
Resting EEG partial coherence demonstrates increased γ-range central functional connectivity in amnestic mild cognitive impairment.
Brain Research. 2025; 1867:149973.
View (DOI)Full Publication List
De Santis F, Rosignoli C, Onofri A, et al. (incl. Apostolakopoulou L)
Diagnostic tests and headache misdiagnoses in individuals with resistant and refractory migraine — data from the REFINE study.
Cephalalgia. 2026; 46.
View (DOI)Vlachos I, Moschovos C, Apostolakopoulou L, et al.
Resting EEG partial coherence demonstrates increased γ-range central functional connectivity in amnestic mild cognitive impairment.
Brain Research. 2025; 1867:149973.
View (DOI)Rosignoli C, Ornello R, Caponnetto V, et al. (incl. Apostolakopoulou L)
Resistant and refractory migraine — two different entities with different comorbidities? Results from the REFINE study.
The Journal of Headache and Pain. 2024; 25:212.
View (DOI)Apostolakopoulou L, Bosque-Varela P, Rossini F, O'Sullivan C, Löscher W, Kuchukhidze G, Trinka E.
Intravenous topiramate for seizure emergencies — first in human case report.
Epilepsy & Behavior. 2023; 142:109158.
View (DOI)Atalar AÇ, Acarlı ANÖ, Baykan B, et al. (incl. Apostolakopoulou L)
COVID-19 vaccination-related headache showed two different clusters in the long-term course: a prospective multicentre follow-up study (COVA-Head Study).
The Journal of Headache and Pain. 2023; 24(1):132.
View (DOI)Vittas S, Bisba M, Christopoulou G, Apostolakopoulou L, Pons R, Constantoulakis P.
A Case of Class I 17p13.3 Microduplication Syndrome with Unilateral Hearing Loss.
Genes. 2023; 14(7):1333.
View (DOI)Castaldo M, Waliszewska-Prosół M, Koutsokera M, et al. (incl. Apostolakopoulou L); EHF-SAS.
Headache onset after vaccination against SARS-CoV-2: a systematic literature review and meta-analysis.
The Journal of Headache and Pain. 2022; 23(1):41.
View (DOI)Apostolakopoulou L, Tountopoulou A, Pantou E.
Bilateral wallerian degeneration of middle cerebellar peduncles following unilateral pontine infarction.
Journal of Clinical Images and Medical Case Reports. 2022; 3(4):1777.
Zouvelou V, Yubero D, Apostolakopoulou L, et al.
The genetic etiology in cerebral palsy mimics: the results from a Greek tertiary care center.
European Journal of Paediatric Neurology. 2019; 23(3):427-437.
View (DOI)Clinical Studies
REFINE Study
Multicentre observational study on refractory migraine.
COVAHEAD Study
International study on the effect of SARS-CoV-2 vaccination on the course of primary headaches.
Migrainous Infarcts & Stroke Registry
Clinical-imaging correlation study of migrainous infarcts with ischaemic strokes.
Professional Memberships
- Athens Medical Association
- Hellenic Neurological Society
- Hellenic Headache Society
- European Academy of Neurology (EAN)
- International League Against Epilepsy (ILAE)
Conference Activity
She has delivered numerous oral presentations and posters at Greek and international congresses of Neurology, Headache and Epilepsy, on topics including:
- Surgical management of drug-resistant epilepsy
- EEG findings in critically ill patients
- Migraine and migrainous infarction
- Encephalitis and epilepsy
- Paroxysmal episodes in the 1p36 genetic syndrome
- COVID-19-related headache
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